The macrophage scavenger receptor A is host-protective in experimental meningococcal septicaemia.

Macrophage Scavenger Receptor A (SR-A) is a major non-opsonic receptor for Neisseria meningitidis on mononuclear phagocytes in vitro, and the surface proteins NMB0278, NMB0667, and NMB1220 have been identified as ligands for SR-A. In this study we ascertain the in vivo role of SR-A in the recognitio...

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Bibliographic Details
Main Authors: Annette Plüddemann, J Claire Hoe, Katherine Makepeace, E Richard Moxon, Siamon Gordon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-02-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000297&type=printable
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