Role of RGS17 in cisplatin-induced cochlear inflammation and ototoxicity via caspase-3 activation

Cisplatin is a chemotherapy drug used to treat different solid tumors, including ovarian, bladder, lung, and head and neck cancers. One of its significant side effects is ototoxicity, especially when high doses are required. Cisplatin-induced ototoxicity is associated with increased cochlear cell de...

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Bibliographic Details
Main Authors: Raheem F. H. Al Aameri, Entkhab M. A. Alanisi, Dheyaa Al Sallami, Ian Alberts, Shelley Tischkau, Leonard P. Rybak, Vickram Ramkumar
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1470625/full
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