Exploring the heterogeneity in glioblastoma cellular mechanics using in-vitro assays and atomic force microscopy

Exploring the heterogeneity in glioblastoma cellular mechanics using in-vitro assays and atomic force microscopy

Abstract Glioblastoma multiforme (GBM) is an aggressive brain tumor with limited treatment options and prognosis due to its highly invasive nature and therapy resistance. Investigating the nanomechanical and pathophysiological properties of GBM cells will shed light on tumor behavior. In our study,...

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Bibliographic Details
Main Authors: Nabila Masud, Md Hasibul Hasan Hasib, Bayode Ibironke, Charlotte Block, Jayce Hughes, Andrew Ekpenyong, Anwesha Sarkar
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
Subjects:
Glioblastoma
AFM
Nanomechanical properties
Cancer heterogeneity
Migration
Online Access:https://doi.org/10.1038/s41598-025-04841-4
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https://doi.org/10.1038/s41598-025-04841-4

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