CDH3 promotes the progression of lung adenocarcinoma through driving epithelial-mesenchymal transition progress

CDH3 promotes the progression of lung adenocarcinoma through driving epithelial-mesenchymal transition progress

Abstract Background Cadherin-3 (CDH3) participates in multiple oncogenic processes, but its biological role and mechanisms in lung adenocarcinoma (LUAD) remain inadequately understood. Methods We analyzed CDH3 expression in LUAD versus adjacent normal tissues and assessed its association with patien...

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Bibliographic Details
Main Authors: Wenlin Gong, Fushan Gao, Haihua He, Zhen Zhang, Fei Shao, Yibo Gao, Jie He
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Journal of Translational Medicine
Subjects:
CDH3
Lung adenocarcinoma
EMT
Tumor associated macrophages
Immunotherapy
Online Access:https://doi.org/10.1186/s12967-025-06750-6
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https://doi.org/10.1186/s12967-025-06750-6

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