Dissolution and Pharmacokinetic Studies of Paracetamol-4,4′-Bipyridine Cocrystals Obtained Using Four Methods

Dissolution and Pharmacokinetic Studies of Paracetamol-4,4′-Bipyridine Cocrystals Obtained Using Four Methods

Paracetamol-4,4′-bipyridine cocrystals were synthesized using a solution method, reflux method, grinding method, and ultrasonic method. The structures and properties were characterized through the utilization of single-crystal X-ray diffraction (SXRD), powder X-ray diffraction (PXRD), polarized ligh...

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Bibliographic Details
Main Authors: Xiaoming Zhang, Yejia Huang, Jinliang Li, Yiying Chen, Jialing Lian
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Crystals
Subjects:
paracetamol
cocrystal
synthesis method
dissolution
pharmacokinetics
Online Access:https://www.mdpi.com/2073-4352/15/1/70
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