Trojan‐Horse Strategy Targeting the Gut‐Liver Axis Modulates Gut Microbiome and Reshapes Microenvironment for Orthotopic Hepatocellular Carcinoma Therapy

Trojan‐Horse Strategy Targeting the Gut‐Liver Axis Modulates Gut Microbiome and Reshapes Microenvironment for Orthotopic Hepatocellular Carcinoma Therapy

Abstract Reversing the hepatic inflammatory and immunosuppressive microenvironment caused by gut microbiota‐derived lipopolysaccharides (LPS), accumulating to the liver through the gut‐liver axis, is crucial for suppressing hepatocellular carcinoma (HCC) and metastasis. However, synergistically mani...

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Bibliographic Details
Main Authors: Haochen Yao, Sheng Ma, Juanjuan Huang, Xinghui Si, Ming Yang, Wantong Song, Guoyue Lv, Guoqing Wang
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Advanced Science
Subjects:
gut microbiota
hepatic inflammation
hepatocellular carcinoma
immunotherapy
oral nanomedicine
Online Access:https://doi.org/10.1002/advs.202310002
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https://doi.org/10.1002/advs.202310002

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