Lenalidomide-induced pure red cell aplasia is associated with elevated expression of MHC-I molecules on erythrocytes

Lenalidomide-induced pure red cell aplasia is associated with elevated expression of MHC-I molecules on erythrocytes

Abstract The RVd therapy, combining lenalidomide, bortezomib, and dexamethasone, is a mainstay treatment for multiple myeloma. A multiple myeloma patient developed pure red cell aplasia (PRCA) following RVd treatment, despite the absence of common PRCA triggers. In vitro analyses reveal lenalidomide...

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Main Authors: Qi Hu, Yang Liu, Qiuyu Yue, Shuo Zhou, Xianghong Jin, Fan Lin, Xiao-Jun Huang, Junling Zhuang, Jin Lu, Xiaofei Gao, Hsiang-Ying Lee
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54571-w
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https://doi.org/10.1038/s41467-024-54571-w

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