EARLY AND LATE STAGE PROFILES FOR A CHEMOTAXIS MODEL WITH DENSITY-DEPENDENT JUMP PROBABILITY

In this paper, we derive a chemotaxis model with degenerate diffusion and density-dependent chemotactic sensitivity, and we provide a more realistic description of cell migration process for its early and late stages. Different from the existing studies focusing on the case of non-degenerate diffusi...

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Main Authors: Tianyuan Xu, Shanming Ji, Chunhua Jin, Ming Mei, Jingxue Yin
Format: Article
Language:English
Published: AIMS Press 2018-11-01
Series:Mathematical Biosciences and Engineering
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Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2018062
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author Tianyuan Xu
Shanming Ji
Chunhua Jin
Ming Mei
Jingxue Yin
author_facet Tianyuan Xu
Shanming Ji
Chunhua Jin
Ming Mei
Jingxue Yin
author_sort Tianyuan Xu
collection DOAJ
description In this paper, we derive a chemotaxis model with degenerate diffusion and density-dependent chemotactic sensitivity, and we provide a more realistic description of cell migration process for its early and late stages. Different from the existing studies focusing on the case of non-degenerate diffusion, this model with degenerate diffusion causes us some essential difficulty on the boundedness estimates and the propagation behavior of its compact support. In the presence of logistic damping, for the early stage before tumour cells spread to the whole domain, we first estimate the expanding speed of tumour region as $O(t^{β})$ for $ 0 \lt β \lt \frac{1}{2}$ . Then, for the late stage of cell migration, we further prove that the asymptotic profile of the original system is just its corresponding steady state. The global convergence of the original weak solution to the steady state with exponential rate $O(e^{-ct})$ for some $c \gt 0$ is also obtained.
format Article
id doaj-art-77d02f42077e49d5b500461361fbc803
institution Kabale University
issn 1551-0018
language English
publishDate 2018-11-01
publisher AIMS Press
record_format Article
series Mathematical Biosciences and Engineering
spelling doaj-art-77d02f42077e49d5b500461361fbc8032025-01-24T02:41:08ZengAIMS PressMathematical Biosciences and Engineering1551-00182018-11-011561345138510.3934/mbe.2018062EARLY AND LATE STAGE PROFILES FOR A CHEMOTAXIS MODEL WITH DENSITY-DEPENDENT JUMP PROBABILITYTianyuan Xu0Shanming Ji1Chunhua Jin2Ming Mei3Jingxue Yin4School of Mathematical Sciences, South China Normal University, Guangzhou, Guangdong 510631, ChinaSchool of Mathematics, South China University of Technology, Guangzhou, Guangdong 510641, ChinaSchool of Mathematical Sciences, South China Normal University, Guangzhou, Guangdong 510631, ChinaDepartment of Mathematics, Champlain College Saint-Lambert, Quebec, J4P 3P2, CanadaSchool of Mathematical Sciences, South China Normal University, Guangzhou, Guangdong 510631, ChinaIn this paper, we derive a chemotaxis model with degenerate diffusion and density-dependent chemotactic sensitivity, and we provide a more realistic description of cell migration process for its early and late stages. Different from the existing studies focusing on the case of non-degenerate diffusion, this model with degenerate diffusion causes us some essential difficulty on the boundedness estimates and the propagation behavior of its compact support. In the presence of logistic damping, for the early stage before tumour cells spread to the whole domain, we first estimate the expanding speed of tumour region as $O(t^{β})$ for $ 0 \lt β \lt \frac{1}{2}$ . Then, for the late stage of cell migration, we further prove that the asymptotic profile of the original system is just its corresponding steady state. The global convergence of the original weak solution to the steady state with exponential rate $O(e^{-ct})$ for some $c \gt 0$ is also obtained.https://www.aimspress.com/article/doi/10.3934/mbe.2018062chemotaxis modeldegenerate diffusiondensity-dependent jump probabilityfinite speed propagationtumour invasions modelsporous media diffusion.
spellingShingle Tianyuan Xu
Shanming Ji
Chunhua Jin
Ming Mei
Jingxue Yin
EARLY AND LATE STAGE PROFILES FOR A CHEMOTAXIS MODEL WITH DENSITY-DEPENDENT JUMP PROBABILITY
Mathematical Biosciences and Engineering
chemotaxis model
degenerate diffusion
density-dependent jump probability
finite speed propagation
tumour invasions models
porous media diffusion.
title EARLY AND LATE STAGE PROFILES FOR A CHEMOTAXIS MODEL WITH DENSITY-DEPENDENT JUMP PROBABILITY
title_full EARLY AND LATE STAGE PROFILES FOR A CHEMOTAXIS MODEL WITH DENSITY-DEPENDENT JUMP PROBABILITY
title_fullStr EARLY AND LATE STAGE PROFILES FOR A CHEMOTAXIS MODEL WITH DENSITY-DEPENDENT JUMP PROBABILITY
title_full_unstemmed EARLY AND LATE STAGE PROFILES FOR A CHEMOTAXIS MODEL WITH DENSITY-DEPENDENT JUMP PROBABILITY
title_short EARLY AND LATE STAGE PROFILES FOR A CHEMOTAXIS MODEL WITH DENSITY-DEPENDENT JUMP PROBABILITY
title_sort early and late stage profiles for a chemotaxis model with density dependent jump probability
topic chemotaxis model
degenerate diffusion
density-dependent jump probability
finite speed propagation
tumour invasions models
porous media diffusion.
url https://www.aimspress.com/article/doi/10.3934/mbe.2018062
work_keys_str_mv AT tianyuanxu earlyandlatestageprofilesforachemotaxismodelwithdensitydependentjumpprobability
AT shanmingji earlyandlatestageprofilesforachemotaxismodelwithdensitydependentjumpprobability
AT chunhuajin earlyandlatestageprofilesforachemotaxismodelwithdensitydependentjumpprobability
AT mingmei earlyandlatestageprofilesforachemotaxismodelwithdensitydependentjumpprobability
AT jingxueyin earlyandlatestageprofilesforachemotaxismodelwithdensitydependentjumpprobability