Spatial transcriptomics reveal high T cell and monocyte status as predictive and prognostic markers in pancreatic cancer

Spatial transcriptomics reveal high T cell and monocyte status as predictive and prognostic markers in pancreatic cancer

Abstract Background In the present study, we intended to discover predictive or prognostic factors of pancreatic ductal adenocarcinoma (PDAC). We intended to investigate the differences between PDAC cases that are treated with upfront surgery (UFS) and surgery after neoadjuvant FOLFIRINOX chemothera...

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Main Authors: Yeon Bi Han, Sejoon Lee, Jin-Ok Lee, Se In Jeong, Ki Rim Lee, Soomin Ahn, Kwangrok Jung, Jong-Chan Lee, Yoo-Seok Yoon, Jin-Hyeok Hwang, Ho-Seong Han, Hee Young Na, Jaihwan Kim
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Translational Medicine
Subjects:
Pancreatic cancer
Spatial transcriptomics
Immunohistochemistry
Predictive marker
Prognostic marker
Online Access:https://doi.org/10.1186/s12967-025-06599-9
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https://doi.org/10.1186/s12967-025-06599-9

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