Differential proteomic analysis of human erythroblasts undergoing apoptosis induced by epo-withdrawal.
The availability of Erythropoietin (Epo) is essential for the survival of erythroid progenitors. Here we study the effects of Epo removal on primary human erythroblasts grown from peripheral blood CD34(+) cells. The erythroblasts died rapidly from apoptosis, even in the presence of SCF, and within 2...
Saved in:
| Main Authors: | Stéphanie Pellegrin, Kate J Heesom, Timothy J Satchwell, Bethan R Hawley, Geoff Daniels, Emile van den Akker, Ashley M Toye |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2012-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0038356&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Protein distribution during human erythroblast enucleation in vitro.
by: Amanda J Bell, et al.
Published: (2013-01-01) -
Enhancement of red blood cell transfusion compatibility using CRISPR‐mediated erythroblast gene editing
by: Joseph Hawksworth, et al.
Published: (2018-04-01) -
Erythroblast Enucleation
by: Ganesan Keerthivasan, et al.
Published: (2011-01-01) -
Erythroblast island macrophages and their surface markers
by: Mei Fang, et al.
Published: (2025-05-01) -
Scalable in vitro production of defined mouse erythroblasts.
by: Helena S Francis, et al.
Published: (2022-01-01)