Differential proteomic analysis of human erythroblasts undergoing apoptosis induced by epo-withdrawal.

The availability of Erythropoietin (Epo) is essential for the survival of erythroid progenitors. Here we study the effects of Epo removal on primary human erythroblasts grown from peripheral blood CD34(+) cells. The erythroblasts died rapidly from apoptosis, even in the presence of SCF, and within 2...

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Bibliographic Details
Main Authors: Stéphanie Pellegrin, Kate J Heesom, Timothy J Satchwell, Bethan R Hawley, Geoff Daniels, Emile van den Akker, Ashley M Toye
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0038356&type=printable
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