Impact of thymoquinone on the Nrf2/HO-1 and MAPK/NF-κB axis in mitigating 5-fluorouracil-induced acute kidney injury in vivo
BackgroundChemotherapy-induced organ toxicity is one of the most common toxic effects of 5-fluorouracil (5-FU) in cancer patients. Therefore, new strategies are needed to prevent chemotherapy-induced kidney toxicity. Thymoquinone (TQ), a constituent of the plant Nigella sativa from the family Renunc...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1572095/full |
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