Comparison of spatial transcriptomics technologies using tumor cryosections

Comparison of spatial transcriptomics technologies using tumor cryosections

Abstract Background Spatial transcriptomics technologies are revolutionizing our understanding of intra-tumor heterogeneity and the tumor microenvironment by revealing single-cell molecular profiles within their spatial tissue context. The rapid development of spatial transcriptomics methods, each w...

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Main Authors: Anne Rademacher, Alik Huseynov, Michele Bortolomeazzi, Sina Jasmin Wille, Sabrina Schumacher, Pooja Sant, Denise Keitel, Konstantin Okonechnikov, David R. Ghasemi, Kristian W. Pajtler, Jan-Philipp Mallm, Karsten Rippe
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Genome Biology
Subjects:
Spatial transcriptomics
Visium
RNAscope
Molecular Cartography
Merscope
MERFISH
Online Access:https://doi.org/10.1186/s13059-025-03624-4
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https://doi.org/10.1186/s13059-025-03624-4

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