Changes in the concentration of freely circulating mutant DNA and wild-type DNA of the H3F3А (K27M) gene in the blood and cerebrospinal fluid of children with diffuse midline gliomas during a course of radiation therapy

Changes in the concentration of freely circulating mutant DNA and wild-type DNA of the H3F3А (K27M) gene in the blood and cerebrospinal fluid of children with diffuse midline gliomas during a course of radiation therapy

Purpose of the study. To study the possibility of detecting freely circulating DNA of the H3F3A (K27M) gene in blood plasma and cerebrospinal fluid in the lumbar spine in children with diffuse midline gliomas (DMG) during a course of radiation therapy (RT).Materials and methods. Molecular genetic st...

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Main Authors: O. S. Regentova, V. K. Bozhenko, E. A. Kudinova, T. M. Kulinich, E. L. Dzhikiya, V. V. Kaminskiy, F. F. Antonenko, R. A. Parkhomenko, N. I. Zelinskaya, N. Sidibe, P. V. Polushkin, A. I. Shevtsov, M. A. Bliznichenko, V. A. Solodkiy
Format: Article
Language:Russian
Published: ANO "Perspective of oncology" 2024-09-01
Series:Южно-Российский онкологический журнал
Subjects:
glioma
diffuse median glioma
digital drip pcr
h3f3a
k27m
circulating tumor dna (ctdna)
Online Access:https://www.cancersp.com/jour/article/view/307
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