Analysis of the clinical value and influencing factors of combined detection of tuberculosis-specific cytokines IFN-γ and IL-2 in the diagnosis of active tuberculosis in children and adolescents

Analysis of the clinical value and influencing factors of combined detection of tuberculosis-specific cytokines IFN-γ and IL-2 in the diagnosis of active tuberculosis in children and adolescents

Abstract Objective This study aimed to conduct a combined detection of Mycobacterium tuberculosis (MTB) infection using the tuberculosis (TB)-specific cytokine interferon-γ (IFN-γ) and interleukin-2 (IL-2) release assays in hospitalized children and adolescents with TB, evaluate the clinical value o...

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Bibliographic Details
Main Authors: Jinyu Chen, Bin Deng, Maoying Li, Yuhong Huang, Jing Han, Qiong Li, Li Gao, Lei Chen, Shenjie Tang
Format: Article
Language:English
Published: BMC 2025-08-01
Series:European Journal of Medical Research
Subjects:
Children
Adolescents
Active tuberculosis
IFN-γ
IL-2
Combined detection
Online Access:https://doi.org/10.1186/s40001-025-02895-8
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https://doi.org/10.1186/s40001-025-02895-8

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