An immune suppressive tumor microenvironment in primary prostate cancer promotes tumor immune escape.

An immune suppressive tumor microenvironment in primary prostate cancer promotes tumor immune escape.

<h4>Background</h4>Immunotherapy has demonstrated limited activity in prostate cancer to date. This likely reflects an immune suppressive tumor microenvironment (TME), with previous studies suggesting low PD-L1 expression and a sparse immune cell infiltrate. We aimed to further character...

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Main Authors: Angelyn Anton, Ryan Hutchinson, Christopher M Hovens, Michael Christie, Andrew Ryan, Peter Gibbs, Anthony Costello, Justin Peters, Paul J Neeson, Niall M Corcoran, Ben Tran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0301943
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https://doi.org/10.1371/journal.pone.0301943

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