Evaluation of three mechanisms of action (SGLT2 inhibitors, GLP-1 receptor agonists, and sulfonylureas) in treating type 2 diabetes with heart failure: a systematic review and network meta-analysis of RCTs

ObjectiveWe aimed to evaluate and compare the efficacy and safety of three antidiabetic drug classes—SGLT2 inhibitors, GLP-1 receptor agonists, and sulfonylureas—in patients with type 2 diabetes mellitus (T2DM) complicated by heart failure (HF). We focused on their differential effects on both cardi...

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Bibliographic Details
Main Authors: Huize Gao, Qian Wei, Anqi Zou, Keying Yu, Da Song, Jian Li, Huize Han, Aidong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Endocrinology
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Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1562815/full
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