Protein Nitration in Patients with Mitochondrial Diseases

Protein Nitration in Patients with Mitochondrial Diseases

Mitochondrial diseases are complex disorders caused by nuclear or mitochondrial DNA mutations, leading to oxidative phosphorylation deficiency and excessive production of reactive oxygen species (ROS). While ROS have been well established in the pathogenesis of these diseases, the role of reactive n...

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Main Authors: Jomênica B. Livramento, Gabriela S. Rodrigues, Jean Faber, Luis A. de Souza Filho, Felipo V. Moura, Camila D. S. Barros, Wladimir B. V. R. Pinto, Beny Schmidt, Acary S. B. Oliveira, Beatriz H. Kiyomoto, Célia H. Tengan
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Antioxidants
Subjects:
nitric oxide
mitochondrial diseases
protein nitration
oxidative stress
nitrative stress
mitochondrial DNA (mtDNA)
Online Access:https://www.mdpi.com/2076-3921/14/2/211
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