Enhancing colorimetric loop-mediated isothermal amplification speed and sensitivity with guanidine chloride

Enhancing colorimetric loop-mediated isothermal amplification speed and sensitivity with guanidine chloride

Loop-mediated isothermal amplification (LAMP) is a versatile technique for detection of target DNA and RNA, enabling rapid molecular diagnostic assays with minimal equipment. The global SARS-CoV-2 pandemic has presented an urgent need for new and better diagnostic methods, with colorimetric LAMP uti...

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Bibliographic Details
Main Authors: Yinhua Zhang, Guoping Ren, Jackson Buss, Andrew J Barry, Gregory C Patton, Nathan A Tanner
Format: Article
Language:English
Published: Taylor & Francis Group 2020-09-01
Series:BioTechniques
Subjects:
high-throughput screening
isothermal amplification
LAMP
molecular diagnostics
PCR
SARS-CoV-2
Online Access:https://www.future-science.com/doi/10.2144/btn-2020-0078
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https://www.future-science.com/doi/10.2144/btn-2020-0078

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