Directed evolution provides insight into conformational substrate sampling by SrtA.
The Sortase family of transpeptidases are found in numerous gram-positive bacteria and involved in divergent physiological processes including anchoring of surface proteins to the cell wall as well as pili assembly. As essential proteins, sortase enzymes have been the focus of considerable interest...
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| Main Authors: | Muna Suliman, Vishaka Santosh, Tom C M Seegar, Annamarie C Dalton, Kathryn M Schultz, Candice S Klug, William A Barton |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2017-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0184271&type=printable |
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