Directed evolution provides insight into conformational substrate sampling by SrtA.

The Sortase family of transpeptidases are found in numerous gram-positive bacteria and involved in divergent physiological processes including anchoring of surface proteins to the cell wall as well as pili assembly. As essential proteins, sortase enzymes have been the focus of considerable interest...

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Bibliographic Details
Main Authors: Muna Suliman, Vishaka Santosh, Tom C M Seegar, Annamarie C Dalton, Kathryn M Schultz, Candice S Klug, William A Barton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0184271&type=printable
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