Dose-Dependent Cellular Phenotypic Change Induced by <sup>177</sup>Lu-Oxodotreotide Treatment in IMR-32 Cells

Dose-Dependent Cellular Phenotypic Change Induced by <sup>177</sup>Lu-Oxodotreotide Treatment in IMR-32 Cells

<b>Objectives</b>: Beta-emitting radionuclide therapy, exemplified by <sup>177</sup>Lu-Oxodotreotide (Lutathera<sup>®</sup>), enables targeted treatment of neuroendocrine tumors by delivering β-radiation to tumor cells. However, the dose-dependent molecular mechan...

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Bibliographic Details
Main Authors:	Shuai Xue, Xiaobei Zheng, Bingbing Pu, Xiao Li, Jun Li, Meng Huang, Jian Yang, Jingjing Lou
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Series:	Biomedicines
Subjects:	<sup>177</sup>Lu-Oxodotreotide β-emitting therapeutics cell damage dose dependent
Online Access:	https://www.mdpi.com/2227-9059/13/7/1543
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