Dose-Dependent Cellular Phenotypic Change Induced by <sup>177</sup>Lu-Oxodotreotide Treatment in IMR-32 Cells

<b>Objectives</b>: Beta-emitting radionuclide therapy, exemplified by <sup>177</sup>Lu-Oxodotreotide (Lutathera<sup>®</sup>), enables targeted treatment of neuroendocrine tumors by delivering β-radiation to tumor cells. However, the dose-dependent molecular mechan...

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Bibliographic Details
Main Authors: Shuai Xue, Xiaobei Zheng, Bingbing Pu, Xiao Li, Jun Li, Meng Huang, Jian Yang, Jingjing Lou
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomedicines
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Online Access:https://www.mdpi.com/2227-9059/13/7/1543
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