MDNN-DTA: a multimodal deep neural network for drug-target affinity prediction

Determining drug-target affinity (DTA) is a pivotal step in drug discovery, where in silico methods can significantly improve efficiency and reduce costs. Artificial intelligence (AI), especially deep learning models, can automatically extract high-dimensional features from the biological sequences...

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Bibliographic Details
Main Authors: Xu Gao, Mengfan Yan, Chengwei Zhang, Gang Wu, Jiandong Shang, Congxiang Zhang, Kecheng Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Genetics
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Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1527300/full
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