Design and evaluation of a tripartite chemogenetic fluorescent reporter for visualizing ternary protein complexes

Abstract Most cellular processes are carried out by multiprotein assemblies. Although various molecular tools exist to visualize binary protein interactions in live cells, the visualization of multiprotein complexes remains a challenge. Here, we report the engineering of a complementation-based appr...

Full description

Saved in:
Bibliographic Details
Main Authors: Sara Bottone, Fanny Broch, Antoine Gedeon, Aurélien Brion, Lina El Hajji, Hela Benaissa, Arnaud Gautier
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62241-8
Tags: Add Tag
No Tags, Be the first to tag this record!