IGF-1-Overexpressing Mesenchymal Stem/Stromal Cells Promote Immunomodulatory and Proregenerative Effects in Chronic Experimental Chagas Disease

IGF-1-Overexpressing Mesenchymal Stem/Stromal Cells Promote Immunomodulatory and Proregenerative Effects in Chronic Experimental Chagas Disease

Mesenchymal stem/stromal cells (MSCs) have been investigated for the treatment of diseases that affect the cardiovascular system, including Chagas disease. MSCs are able to promote their beneficial actions through the secretion of proregenerative and immunomodulatory factors, including insulin-like...

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Main Authors: Daniela N. Silva, Bruno S. F. Souza, Carine M. Azevedo, Juliana F. Vasconcelos, Paloma G. de Jesus, Malena S. Feitoza, Cassio S. Meira, Gisele B. Carvalho, Bruno Raphael Cavalcante, Ricardo Ribeiro-dos-Santos, Milena B. P. Soares
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2018/9108681
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http://dx.doi.org/10.1155/2018/9108681

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