Engineering of ATP synthase for enhancement of proton-to-ATP ratio

Engineering of ATP synthase for enhancement of proton-to-ATP ratio

Abstract FoF1-ATP synthase (FoF1) interconverts the energy of the proton motive force (pmf) and that of ATP through the mechanical rotation. The H+/ATP ratio, one of the most crucial parameters in bioenergetics, varies among species due to differences in the number of H+-binding c-subunits, resultin...

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Main Authors: Hiroshi Ueno, Kiyoto Yasuda, Norie Hamaguchi-Suzuki, Riku Marui, Naruhiko Adachi, Toshiya Senda, Takeshi Murata, Hiroyuki Noji
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61227-w
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https://doi.org/10.1038/s41467-025-61227-w

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