Unilateral Subconjunctival and Retrobulbar Hemorrhage Secondary to Brodifacoum Toxicity in a Dog

An 8-year-old spayed female mixed-breed dog was presented for an acute onset of bleeding around the left eye. Mild exophthalmos and massive subconjunctival hemorrhage on the globe and nictitating membrane were present in the left eye. Retrobulbar hemorrhage was suspected, and pain was implied on ope...

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Main Authors: Sonia E. Kuhn, Diane V. H. Hendrix
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Veterinary Medicine
Online Access:http://dx.doi.org/10.1155/2013/417808
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author Sonia E. Kuhn
Diane V. H. Hendrix
author_facet Sonia E. Kuhn
Diane V. H. Hendrix
author_sort Sonia E. Kuhn
collection DOAJ
description An 8-year-old spayed female mixed-breed dog was presented for an acute onset of bleeding around the left eye. Mild exophthalmos and massive subconjunctival hemorrhage on the globe and nictitating membrane were present in the left eye. Retrobulbar hemorrhage was suspected, and pain was implied on opening of the mouth because the patient resisted and vocalized. No other abnormalities were found on ophthalmic or physical examination. Further questioning of the owner confirmed potential brodifacoum ingestion, and prothrombin time and partial thromboplastin time were both markedly elevated. Treatment with oral vitamin K1 was implemented, and the subconjunctival hemorrhage was significantly improved within a few days of instituting treatment. All clinical signs of coagulopathy were completely resolved within 4 weeks of presentation. Coagulopathy secondary to brodifacoum ingestion can manifest as severe unilateral bulbar and nictitating membrane subconjunctival hemorrhage and exophthalmos due to retrobulbar hemorrhage without other clinical signs.
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series Case Reports in Veterinary Medicine
spelling doaj-art-76bfafc2e2a545d5aef13e7acec9970d2025-02-03T01:22:39ZengWileyCase Reports in Veterinary Medicine2090-70012090-701X2013-01-01201310.1155/2013/417808417808Unilateral Subconjunctival and Retrobulbar Hemorrhage Secondary to Brodifacoum Toxicity in a DogSonia E. Kuhn0Diane V. H. Hendrix1Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, 2407 River Drive, Knoxville, TN 37996, USADepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, 2407 River Drive, Knoxville, TN 37996, USAAn 8-year-old spayed female mixed-breed dog was presented for an acute onset of bleeding around the left eye. Mild exophthalmos and massive subconjunctival hemorrhage on the globe and nictitating membrane were present in the left eye. Retrobulbar hemorrhage was suspected, and pain was implied on opening of the mouth because the patient resisted and vocalized. No other abnormalities were found on ophthalmic or physical examination. Further questioning of the owner confirmed potential brodifacoum ingestion, and prothrombin time and partial thromboplastin time were both markedly elevated. Treatment with oral vitamin K1 was implemented, and the subconjunctival hemorrhage was significantly improved within a few days of instituting treatment. All clinical signs of coagulopathy were completely resolved within 4 weeks of presentation. Coagulopathy secondary to brodifacoum ingestion can manifest as severe unilateral bulbar and nictitating membrane subconjunctival hemorrhage and exophthalmos due to retrobulbar hemorrhage without other clinical signs.http://dx.doi.org/10.1155/2013/417808
spellingShingle Sonia E. Kuhn
Diane V. H. Hendrix
Unilateral Subconjunctival and Retrobulbar Hemorrhage Secondary to Brodifacoum Toxicity in a Dog
Case Reports in Veterinary Medicine
title Unilateral Subconjunctival and Retrobulbar Hemorrhage Secondary to Brodifacoum Toxicity in a Dog
title_full Unilateral Subconjunctival and Retrobulbar Hemorrhage Secondary to Brodifacoum Toxicity in a Dog
title_fullStr Unilateral Subconjunctival and Retrobulbar Hemorrhage Secondary to Brodifacoum Toxicity in a Dog
title_full_unstemmed Unilateral Subconjunctival and Retrobulbar Hemorrhage Secondary to Brodifacoum Toxicity in a Dog
title_short Unilateral Subconjunctival and Retrobulbar Hemorrhage Secondary to Brodifacoum Toxicity in a Dog
title_sort unilateral subconjunctival and retrobulbar hemorrhage secondary to brodifacoum toxicity in a dog
url http://dx.doi.org/10.1155/2013/417808
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