A simple quantitative model for the prediction of exposure of renally excreted drugs in pregnant women: a comparison with whole body PBPK model
Aim: The objective of this study was to develop a simple quantitative model (SQM) to predict maximum plasma concentration (Cmax) and the area under the curve (AUC) of renally excreted drugs (n = 16) in pregnant women from non-pregnant women. Methods: The SQM was developed using 6 physiological param...
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| Main Author: | |
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| Format: | Article |
| Language: | English |
| Published: |
Open Exploration
2025-07-01
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| Series: | Exploration of Drug Science |
| Subjects: | |
| Online Access: | https://www.explorationpub.com/uploads/Article/A1008115/1008115.pdf |
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