The excretion study of a new derivative of 4,5-dihydroisoxazole-5-carboxamide

Introduction. The new selective inhibitor of PAR-2 receptors, 3-(2-butyl-5-chloro-1H-imidazole-4-yl)-N-[4-methoxy-3-(trifluoromethyl)phenyl]-4,5-dihydro-1,2-oxazole-5-carboxamide (R004), is at the stage of preclinical trail. The excretion of R004 and its metabolites has not been studied before.Aim....

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Bibliographic Details
Main Authors: I. I. Yaichkov, M. K. Korsakov, N. N. Volkhin, V. E. Zaykova, O. E. Lasaraynz
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2025-06-01
Series:Разработка и регистрация лекарственных средств
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Online Access:https://www.pharmjournal.ru/jour/article/view/2054
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