Sex differences in the mediating role of brain-derived neurotrophic factor between inflammation and memory in cirrhotic patients with minimal hepatic encephalopathy

Sex differences in the mediating role of brain-derived neurotrophic factor between inflammation and memory in cirrhotic patients with minimal hepatic encephalopathy

Minimal hepatic encephalopathy (MHE) affects attention, visuo-motor coordination, and visual perception, with mixed evidence on its impact on memory. Brain-derived neurotrophic factor (BDNF) is associated with memory dysfunction, and plays a crucial role in modulating neuroplasticity. This study inv...

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Main Authors: Daniela Batallas, Juan José Gallego, Franc Casanova-Ferrer, Adriá López-Gramaje, Pablo Rivas-Diaz, Javier Megías, Desamparados Escudero-García, Lucía Durbán, Salvador Benlloch, Amparo Urios, Vanesa Hidalgo, Alicia Salvador, Carmina Montoliu
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
BDNF
IL-18
IL-15
Declarative memory
Minimal hepatic encephalopathy
sex differences
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354625000560
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