Mouse SPAG6L, a Key Cytoskeleton Modulator Essential for Male Germ Cell Development, Is Not Required for Sertoli Cell Function

Mouse SPAG6L, a Key Cytoskeleton Modulator Essential for Male Germ Cell Development, Is Not Required for Sertoli Cell Function

Mouse sperm-associated antigen 6-like (SPAG6L) evolved from SPAG6, the mammalian ortholog of Chlamydomonas PF16, which is localized in the central apparatus of the motile cilia and is essential for ciliary motility. Even though the amino acid sequences of the two SPAG6 proteins are highly similar, t...

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Bibliographic Details
Main Authors: Tao Li, Wei Li, Cheng Zheng, Jannette M. Dufour, William H. Walker, Shuiqiao Yuan, Zhibing Zhang
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Cells
Subjects:
<i>Spag6l</i>
axoneme
central apparatus
cilia
Sertoli cells
spermatogenesis
Online Access:https://www.mdpi.com/2073-4409/14/11/783
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