Chronic NO Restriction in Hypertensive Rats Increases Abdominal but Not Thoracic Aortic Intrinsic Stiffness via an Augmentation in Profibrotic Materials

The spontaneously hypertensive rat model with reduced NO synthesis (SHRLN) shares features with aging and hypertension in humans, among other a severe aortic stiffening. The present in vivo study aimed to compare thoracic (TA) and abdominal (AA) aortic stiffness in the SHRLN (treated 5 weeks with L-...

Full description

Saved in:
Bibliographic Details
Main Authors: George Lindesay, Yvonnick Bézie, Christophe Ragonnet, Véronique Duchatelle, Marc Isabelle, Nicole Villeneuve, Christine Vayssettes-Courchay
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.1155/2019/8070198
Tags: Add Tag
No Tags, Be the first to tag this record!