Advanced spectrophotometric chemometric methods for resolving the binary mixture of doxylamine succinate and pyridoxine hydrochloride

Advanced spectrophotometric chemometric methods for resolving the binary mixture of doxylamine succinate and pyridoxine hydrochloride

The prediction power of partial least squares (PLS) and multivariate curve resolution-alternating least squares (MCR-ALS) methods have been studied for simultaneous quantitative analysis of the binary drug combination - doxylamine succinate and pyridoxine hydrochloride. Analysis of first-order UV ov...

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Bibliographic Details
Main Authors: Katsarov Plamen, Gergov Georgi, Alin Aylin, Pilicheva Bissera, Al-Degs Yahya, Simeonov Vasil, Kassarova Margarita
Format: Article
Language:English
Published: Sciendo 2018-03-01
Series:Acta Pharmaceutica
Subjects:
doxylamine succinate
pyridoxine hydrochloride
binary mixture
partial least squares (pls)
partial robust m-regression (prm)
multivariate curve resolution-alternative least squares (mcr-als)
Online Access:https://doi.org/10.2478/acph-2018-0008
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https://doi.org/10.2478/acph-2018-0008

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