Functionality and translation fidelity characterization of mRNA vaccines using platform based mass spectrometry detection
Abstract The success of mRNA-based therapeutics and vaccines is attributed to their rapid development, adaptability, and scalable production. Modified ribonucleotides like N1-methylpseudouridine enhance stability and reduce immunogenicity but were recently found to induce cellular immunity to off-ta...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-02-01
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| Series: | npj Vaccines |
| Online Access: | https://doi.org/10.1038/s41541-025-01082-4 |
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