Protein O-fucosyltransferase 1 promotes PD-L1 stability to drive immune evasion and directs liver cancer to immunotherapy

Background and aims The immunosuppressive tumor microenvironment (TME) plays an essential role in cancer progression and immunotherapy response. Despite the considerable advancements in cancer immunotherapy, the limited response to immune checkpoint blockade (ICB) therapies in patients with hepatoce...

Full description

Saved in:
Bibliographic Details
Main Authors: Fan Wang, Yu Tong, Qiang Xia, Linfeng Li, Wenyun Guo, Zijun Zhu, Qianyu Li, Yifei Qian, Songling Li, Yanfeng Liu
Format: Article
Language:English
Published: BMJ Publishing Group 2024-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/12/6/e008917.full
Tags: Add Tag
No Tags, Be the first to tag this record!