Genetic correlations and causal associations between BMI, HDL-C, and postoperative infections: a two-sample Mendelian randomization study

Genetic correlations and causal associations between BMI, HDL-C, and postoperative infections: a two-sample Mendelian randomization study

Abstract Infections are serious postoperative complications, and strongly affects the mortality and prognosis of patients. Body mass index (BMI) and lipids are factors in postoperative infection, but a causal relationship has not been know. In this Mendelian randomization (MR) study, we utilized gen...

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Bibliographic Details
Main Authors: Tao Yang, Zhe Chen, Daiyin Cao, Wenliang Song, Jinlong Jiang, Xiaoxun Ma, Zhi Mao, Xiangdong Guan, Jianfeng Wu, Rui Shi, Xiang Si
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
High density lipoprotein
Body mass index
Postoperative infection
Linkage disequilibrium score regression
Mendelian randomization
Online Access:https://doi.org/10.1038/s41598-025-95812-2
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https://doi.org/10.1038/s41598-025-95812-2

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