The CD8 and CD4 T-cell response against Kaposi's sarcoma-associated herpesvirus is skewed towards early and late lytic antigens.

The CD8 and CD4 T-cell response against Kaposi's sarcoma-associated herpesvirus is skewed towards early and late lytic antigens.

Kaposi's sarcoma-associated herpesvirus (KSHV) is causally related to Kaposi's sarcoma (KS), the most common malignancy in untreated individuals with HIV/AIDS. The adaptive T-cell immune response against KSHV has not been fully characterized. To achieve a better understanding of the antige...

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Bibliographic Details
Main Authors: Rebecca C Robey, Dimitrios Lagos, Fiona Gratrix, Stephen Henderson, Nick C Matthews, Richard J Vart, Mark Bower, Chris Boshoff, Frances M Gotch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0005890&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0005890&type=printable

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