Transcriptional profiling of human peripheral blood mononuclear cells in household contacts of pulmonary tuberculosis patients provides insights into mechanisms of Mycobacterium tuberculosis control and elimination

Transcriptional profiling of human peripheral blood mononuclear cells in household contacts of pulmonary tuberculosis patients provides insights into mechanisms of Mycobacterium tuberculosis control and elimination

Household contacts (HHCs) of patients with active tuberculosis (ATB) are at higher risk of Mycobacterium tuberculosis (M. tuberculosis) infection. However, the immune factors responsible for different defense responses in HHCs are unknown. Hence, we aimed to evaluate transcriptome signatures in huma...

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Bibliographic Details
Main Authors: Xiao Qi, Qingluan Yang, Jianpeng Cai, Jing Wu, Yan Gao, Qiaoling Ruan, Lingyun Shao, Jun Liu, Xueshi Zhou, Wenhong Zhang, Ning Jiang, Sen Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Emerging Microbes and Infections
Subjects:
Household contacts
peripheral blood mononuclear cell
RNA sequence
tuberculosis
latent tuberculosis infection
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2023.2295387
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https://www.tandfonline.com/doi/10.1080/22221751.2023.2295387

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