Imbalance of redox homeostasis and altered cellular signaling induced by the metal complexes of terpyridine

Abstract Compounds that can induce oxidative stress in cancer cells while remaining nontoxic to healthy cells are extremely promising for potential anticancer drugs. 2,2′:6′,2′′-terpyridine-metal complexes possess these properties. The high level of activity (IC50 = 0.605 µM) of 2,2′:6′,2′′-terpyrid...

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Bibliographic Details
Main Authors: Katarzyna Malarz, Patryk Ziola, Dawid Zych, Patryk Rurka, Anna Mrozek-Wilczkiewicz
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-77575-4
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