Impact of age on the cerebrovascular proteomes of wild-type and Tg-SwDI mice.
The structural integrity of cerebral vessels is compromised during ageing. Abnormal amyloid (Aβ) deposition in the vasculature can accelerate age-related pathologies. The cerebrovascular response associated with ageing and microvascular Aβ deposition was defined using quantitative label-free shotgun...
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| Main Authors: | James L Searcy, Thierry Le Bihan, Natalia Salvadores, James McCulloch, Karen Horsburgh |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089970&type=printable |
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