Impact of age on the cerebrovascular proteomes of wild-type and Tg-SwDI mice.

The structural integrity of cerebral vessels is compromised during ageing. Abnormal amyloid (Aβ) deposition in the vasculature can accelerate age-related pathologies. The cerebrovascular response associated with ageing and microvascular Aβ deposition was defined using quantitative label-free shotgun...

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Bibliographic Details
Main Authors: James L Searcy, Thierry Le Bihan, Natalia Salvadores, James McCulloch, Karen Horsburgh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089970&type=printable
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