A retrospective cohort study of 122 dogs treated for hypercortisolism: low-dose dexamethasone suppression test sensitivity and comparative outcomes in response to mitotane or trilostane

A retrospective cohort study of 122 dogs treated for hypercortisolism: low-dose dexamethasone suppression test sensitivity and comparative outcomes in response to mitotane or trilostane

ABSTRACT Spontaneous hypercortisolism (HC), a prevalent endocrinopathy among elderly dogs, is mainly confirmed by the low dexamethasone dose suppression test (LDDST). However, its diagnostic sensitivity in Brazil is anecdotally reported low compared with published literature. Medical treatment with...

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Bibliographic Details
Main Authors: M.M. Marçal, S.F.M. Martins, C.R. Barbieri, T.B. Nogueira, Á.G. Pöppl
Format: Article
Language:English
Published: Universidade Federal de Minas Gerais 2025-07-01
Series:Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Subjects:
Cushing´s syndrome
hyperadrenocorticism
diagnostic test
false-negative
survival
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352025000400101&lng=en&tlng=en
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