Pathway and protein channel engineering of Bacillus subtilis for improved production of desthiobiotin and biotin

Pathway and protein channel engineering of Bacillus subtilis for improved production of desthiobiotin and biotin

Biotin (vitamin B7) is a crucial cofactor for various metabolic processes and has significant applications in pharmaceuticals, cosmetics, and animal feed. Bacillus subtilis, a well-studied Gram-positive bacterium, presents a promising host for biotin production due to its Generally Recognized as Saf...

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Bibliographic Details
Main Authors: Yue Wu, Guang-Qing Du, Dong-Han Ma, Jin-Long Li, Huan Fang, Hui-Na Dong, Zhao-Xia Jin, Da-Wei Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-03-01
Series:Synthetic and Systems Biotechnology
Subjects:
Biotin
Bacillus subtilis
Biotin synthase
Ribosomal binding site
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X24001431
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