Pyruvate kinase variant of fission yeast tunes carbon metabolism, cell regulation, growth and stress resistance

Pyruvate kinase variant of fission yeast tunes carbon metabolism, cell regulation, growth and stress resistance

Abstract Cells balance glycolysis with respiration to support their metabolic needs in different environmental or physiological contexts. With abundant glucose, many cells prefer to grow by aerobic glycolysis or fermentation. Using 161 natural isolates of fission yeast, we investigated the genetic b...

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Main Authors: Stephan Kamrad, Jan Grossbach, Maria Rodríguez‐López, Michael Mülleder, StJohn Townsend, Valentina Cappelletti, Gorjan Stojanovski, Clara Correia‐Melo, Paola Picotti, Andreas Beyer, Markus Ralser, Jürg Bähler
Format: Article
Language:English
Published: Springer Nature 2020-04-01
Series:Molecular Systems Biology
Subjects:
cellular ageing
fermentation
glycolysis
oxidative stress
respiration
Online Access:https://doi.org/10.15252/msb.20199270
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https://doi.org/10.15252/msb.20199270

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