Preparation and characterization of tadalafil-loaded hydrogel: An in-vivo evaluation of wound healing activity

Preparation and characterization of tadalafil-loaded hydrogel: An in-vivo evaluation of wound healing activity

Tadalafil (TD) is a phosphodiesterase type 5 (PDE-5) inhibitor that has gained attention for its wound healing properties. In this study, a TD-loaded hydrogel was prepared and characterized, and its wound-healing efficacy was evaluated. After preparing the TD hydrogel, its physicochemical properties...

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Main Authors: Anita Sadat Haji Seyed Javadi Pajouhi, Amir Larki-Harcheghani, Mojdeh Mohammadi, Sajjad Makhdoomi, Alireza Nourian, Katayoun Derakhshandeh
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:Pharmaceutical Science Advances
Subjects:
Tadalafil
Hydrogel
Wound healing
Hydroxyproline
Phosphodiesterase type 5 inhibitor
Online Access:http://www.sciencedirect.com/science/article/pii/S2773216925000042
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