Therapeutic drug monitoring of methotrexate and its metabolites in the red blood cells and mononuclear cells of patients with rheumatoid arthritis

Therapeutic drug monitoring of methotrexate and its metabolites in the red blood cells and mononuclear cells of patients with rheumatoid arthritis

Objective: to assess the time course of changes in the concentration of methotrexate (MTX) and its main metabolites in the red blood cells (RBC) and mononuclear cells (MNC) of patients with rheumatoid arthritis (RA), by taking into account individual characteristics (age, statin therapy, and smoking...

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Bibliographic Details
Main Authors: G. I. Gridneva, Yu. V. Muravyev, N. V. Baimeeva, V. S. Sygyrta, S. I. Glukhova, I. A. Guseva, E. Yu. Samarkina, E. S. Aronova, A. V. Kudryavtseva
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2020-11-01
Series:Современная ревматология
Subjects:
therapeutic drug monitoring
methotrexate
rheumatoid arthritis
Online Access:https://mrj.ima-press.net/mrj/article/view/1069
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