Causal models and prediction in cell line perturbation experiments

Causal models and prediction in cell line perturbation experiments

Abstract In cell line perturbation experiments, a collection of cells is perturbed with external agents and responses such as protein expression measured. Due to cost constraints, only a small fraction of all possible perturbations can be tested in vitro. This has led to the development of computati...

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Bibliographic Details
Main Authors: James P. Long, Yumeng Yang, Shohei Shimizu, Thong Pham, Kim-Anh Do
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Bioinformatics
Subjects:
Causal inference
Prediction
Perturbation biology
Systems biology
Online Access:https://doi.org/10.1186/s12859-024-06027-7
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https://doi.org/10.1186/s12859-024-06027-7

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