Xenogeneic-free platform for the isolation and scalable expansion of human bladder smooth muscle cells

Xenogeneic-free platform for the isolation and scalable expansion of human bladder smooth muscle cells

Introduction: Smooth muscle cells (SMC) play a crucial role in bladder tissue engineering strategies. Scalable, Good Manufacturing Practice (GMP)-compliant platforms are essential for producing clinically relevant cell numbers. Materials & Methods: A gamma-irradiated human platelet lysate (H...

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Main Authors: Teresa Franchi-Mendes, Marília Silva, Maria Catarina Carreira, Ana Luísa Cartaxo, Paulo Vale, Panagiotis Karakaidos, Apostolos Klinakis, Ana Fernandes-Platzgummer, Cláudia L. da Silva
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Biotechnology Reports
Subjects:
Bladder tissue engineering
Smooth muscle cells
Xeno(geneic)-free
Microcarrier-based expansion
Online Access:http://www.sciencedirect.com/science/article/pii/S2215017X25000050
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