Accumulation of advanced oxidative protein products exacerbate satellite glial cells activation and neuropathic pain

Accumulation of advanced oxidative protein products exacerbate satellite glial cells activation and neuropathic pain

Abstract Background Neuropathic pain (NP) is a debilitating condition caused by lesion or dysfunction in the somatosensory nervous system. Accumulation of advanced oxidation protein products (AOPPs) is implicated in mechanical hyperalgesia. However, the effects of AOPPs on NP remain unclear. Methods...

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Main Authors: Chen Tu, Shi-Cheng Wang, Meng-Xuan Dai, Si-Qi Lai, Zhi-Wei Huang, Yong-Peng Yu, Yun-Biao Chen, Ji-Huan Zeng, Liang Wang, Zhao-Ming Zhong
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Molecular Medicine
Subjects:
AOPPs
SGCs
RAGE
Inflammation
Neuropathic pain
Online Access:https://doi.org/10.1186/s10020-025-01076-x
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https://doi.org/10.1186/s10020-025-01076-x

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